healty meal, low carbs meals, keto meal

Mac and Cheese Meatloaf Casserole


Mac and Cheese Meatloaf Casserole combines two classic comfort foods into one delicious, hearty dish. This casserole features a flavorful meatloaf base topped with creamy, cheesy macaroni and cheese. Perfect for family dinners or gatherings, this dish is sure to be a hit. Let’s dive into the step-by-step recipe to create this ultimate comfort food casserole.



  • 2 cups milk
  • 30 Ritz crackers, crushed
  • 1 cup BBQ sauce
  • 1 teaspoon pepper
  • 10.5 oz can of cheddar cheese soup
  • 2 cups shredded mozzarella cheese
  • 2 cups shredded cheddar cheese
  • 3 cups uncooked macaroni noodles
  • 1 teaspoon salt
  • 1 cup ketchup
  • 1 tablespoon onion powder
  • 2 large eggs
  • 2 lbs ground beef
  • 1 packet onion soup mix
  • 1 tablespoon garlic powder


Step 1: Prepare the Meatloaf Base

  1. Preheat Oven:
    • Preheat your oven to 350°F (175°C).
  2. Mix Meatloaf Ingredients:
    • In a large bowl, combine the ground beef, crushed Ritz crackers, eggs, onion soup mix, garlic powder, onion powder, salt, and pepper. Mix until well combined.
  3. Form Meatloaf:
    • Press the meatloaf mixture into the bottom of a greased 9×13-inch baking dish, creating an even layer.
  4. Add Toppings:
    • Spread the ketchup and BBQ sauce evenly over the top of the meatloaf layer.

Step 2: Cook the Macaroni

  1. Boil Macaroni:
    • Cook the macaroni noodles according to the package instructions until al dente. Drain and set aside.

Step 3: Prepare the Cheese Sauce

  1. Make Cheese Sauce:
    • In a large saucepan, combine the milk and cheddar cheese soup. Cook over medium heat, stirring constantly, until smooth and heated through.
  2. Add Cheese:
    • Stir in the shredded mozzarella and cheddar cheese until melted and well combined.

Step 4: Combine and Bake

  1. Mix Macaroni and Cheese:
    • Add the cooked macaroni noodles to the cheese sauce, stirring until the noodles are fully coated.
  2. Layer Casserole:
    • Spread the macaroni and cheese mixture evenly over the meatloaf layer in the baking dish.
  3. Bake Casserole:
    • Cover the baking dish with aluminum foil and bake in the preheated oven for 30 minutes. Remove the foil and bake for an additional 10-15 minutes, or until the top is golden and bubbly.

Step 5: Serve

  1. Rest and Serve:
    • Allow the casserole to rest for a few minutes before serving. Slice and serve hot.

Cooking Notes and Tips

  • Cracker Substitute: If you don’t have Ritz crackers, you can use any buttery cracker or breadcrumbs.
  • Cheese Variations: Feel free to use different types of cheese, such as gouda, parmesan, or a cheese blend, for added flavor.
  • Veggie Addition: Add vegetables like diced bell peppers or mushrooms to the meatloaf mixture for extra nutrition.


Spicy Version

  • Add Heat:
    • Add 1-2 teaspoons of hot sauce to the meatloaf mixture and/or cheese sauce for a spicy kick.

Low-Carb Version

  • Replace Macaroni:
    • Use cauliflower florets instead of macaroni noodles for a lower-carb option.

Vegetarian Version

  • Meat Substitute:
    • Use a plant-based ground meat substitute and vegetable broth-based cheese sauce for a vegetarian-friendly version.

Serving Suggestions

With a Green Salad

  • Salad:
    • Serve with a fresh green salad with a light vinaigrette to balance the richness of the casserole.

With Garlic Bread

  • Garlic Bread:
    • Pair with warm garlic bread or a crusty baguette for a complete meal.

With Roasted Vegetables

  • Vegetables:
    • Serve with a side of roasted vegetables like broccoli, carrots, or Brussels sprouts.


Q: Can I make this casserole ahead of time? A: Yes, you can prepare the meatloaf base and the macaroni and cheese separately. Assemble the casserole just before baking. Store in the refrigerator for up to 24 hours before baking.


Q: How do I store leftovers? A: Store any leftover casserole in an airtight container in the refrigerator for up to 3 days. Reheat in the oven or microwave before serving.


Q: Can I freeze this casserole? A: Yes, you can freeze the assembled but unbaked casserole. Wrap it tightly in aluminum foil and plastic wrap, and freeze for up to 3 months. Thaw in the refrigerator overnight and bake as directed.


Q: What if I don’t have cheddar cheese soup? A: You can make a homemade cheese sauce by melting 2 tablespoons of butter, whisking in 2 tablespoons of flour, and gradually adding 1 cup of milk and 1 cup of shredded cheddar cheese until smooth.


Q: Can I use a different type of pasta? A: Yes, you can use other small pasta shapes such as penne, rotini, or shells if you prefer.


Mac and Cheese Meatloaf Casserole is the ultimate comfort food, combining the best of both worlds: savory meatloaf and creamy mac and cheese. This hearty dish is perfect for family dinners and gatherings. Enjoy making and sharing this delicious recipe with your loved ones!